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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine



   follicular lymphoma
  

Disease ID 85
Disease follicular lymphoma
Definition
Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the LYMPH NODES. The nodules resemble to some extent the GERMINAL CENTER of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center B-LYMPHOCYTES.
Synonym
(nodular lymphoma: brill-symmers disease) or (reticulosarcoma - follicular or nodular)
(nodular lymphoma: brill-symmers disease) or (reticulosarcoma - follicular or nodular) (disorder)
[m]brill - symmers' disease
[m]follicular lymphosarcoma nos
[m]giant follicular lymphoma
[m]malignant lymphoma, centroblastic-centrocytic, follicular
[m]malignant lymphoma, centroblastic-centrocytic, follicular (morphologic abnormality)
[m]malignant lymphoma, nodular nos
[m]malignant lymphoma, nodular nos (& [brill - symmers' disease])
[m]malignant lymphoma, nodular nos (& [brill - symmers' disease]) (disorder)
[m]malignant lymphoma, nodular nos (morphologic abnormality)
[m]nodular lymphosarcoma nos
brill - symmers' disease
brill symmers dis
brill symmers disease
brill-symmers disease
disease, brill-symmers
follic lymphoma
follic lymphoma giant
follicle center lymphoma
follicular centre cell lymphoma
follicular low grade b-cell lymphoma
follicular low grade b-cell lymphoma (disorder)
follicular lymphoma (morphologic abnormality)
follicular lymphoma nos
follicular lymphoma, giant
follicular lymphoma: [non-hodgkin's] or [nos]
follicular lymphoma: [non-hodgkin's] or [nos] (disorder)
follicular lymphomas
follicular lymphomas, giant
follicular lymphosarcoma
follicular non-hodgkin lymphoma
follicular non-hodgkin's lymphoma
follicular non-hodgkin's lymphoma (disorder)
germinoblastoma, follicular
giant follic lymphoma
giant follicular lymphoma
giant follicular lymphomas
giant follicular lymphosarcoma
lymphoma follic
lymphoma follicular
lymphoma giant follic
lymphoma, follicular
lymphoma, follicular [disease/finding]
lymphoma, follicular centre cell
lymphoma, follicular, malignant
lymphoma, giant follicular
lymphoma, nodular
lymphomas, follicular
lymphomas, giant follicular
lymphomas, nodular
lymphosarcoma follicular
malignant lymphoma, centroblastic-centrocytic, follicular
malignant lymphoma, centroblastic-centrocytic, follicular (disorder)
malignant lymphoma, centroblastic-centrocytic, follicular (morphologic abnormality)
malignant lymphoma, centroblastic-centrocytic, follicular -retired-
malignant lymphoma, follicle center
malignant lymphoma, follicle center, follicular
malignant lymphoma, follicle centre
malignant lymphoma, follicle centre, follicular
malignant lymphoma, follicular
malignant lymphoma, follicular, nos
malignant lymphoma, lymphocytic, nodular
malignant lymphoma, lymphocytic, nodular, nos
malignant lymphoma, nodular
malignant lymphoma, nodular, nos
nodular lymphocytic lymphoma
nodular lymphoma
nodular lymphoma (brill - symmers disease)
nodular lymphoma (disorder)
nodular lymphoma nos
nodular lymphoma nos (disorder)
nodular lymphoma of unspecified site
nodular lymphoma of unspecified site (disorder)
nodular lymphomas
nodular lymphosarcoma
nodular malignant lymphoma
reticulosarcoma - follicular or nodular
Orphanet
DOID
UMLS
C0024301
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:47)
C0024299  |  lymphoma  |  15
C0024299  |  lymphomas  |  7
C0079731  |  b-cell lymphoma  |  4
C0334634  |  mantle cell lymphoma  |  2
C0079744  |  diffuse large b-cell lymphoma  |  2
C0019829  |  hodgkin lymphoma  |  2
C0030807  |  pemphigus  |  2
C0079731  |  b-cell lymphomas  |  2
C0024305  |  non-hodgkin lymphoma  |  2
C0019829  |  hodgkin's lymphoma  |  2
C0042345  |  varices  |  1
C0039101  |  synovial sarcoma  |  1
C0011991  |  diarrhea  |  1
C0002173  |  follicular mucinosis  |  1
C0001418  |  adenocarcinoma  |  1
C1704214  |  xanthogranuloma  |  1
C0041234  |  chagas disease  |  1
C0040053  |  thrombus  |  1
C0010346  |  crohn's disease  |  1
C0442874  |  neuropathy  |  1
C0037753  |  sparganosis  |  1
C0151313  |  sensory neuropathy  |  1
C0019163  |  viral hepatitis b  |  1
C0949272  |  ileocolitis  |  1
C0472817  |  whim syndrome  |  1
C0152025  |  polyneuropathy  |  1
C0042721  |  viral hepatitis  |  1
C0019158  |  hepatitis  |  1
C0034902  |  pure red cell aplasia  |  1
C0281963  |  red cell aplasia  |  1
C0024301  |  follicular non-hodgkin's lymphoma  |  1
C0043324  |  juvenile xanthogranuloma  |  1
C0006142  |  breast cancer  |  1
C0007104  |  carcinoma of the breast  |  1
C0037889  |  hereditary spherocytosis  |  1
C0024623  |  gastric cancer  |  1
C0079731  |  b-cell non-hodgkin lymphoma  |  1
C0001339  |  acute pancreatitis  |  1
C0019163  |  hepatitis b  |  1
C1134719  |  invasive ductal carcinoma of the breast  |  1
C0341335  |  cmv colitis  |  1
C1261473  |  sarcoma  |  1
C0079734  |  diffuse lymphoma  |  1
C0009319  |  colitis  |  1
C0024305  |  non-hodgkin's lymphoma  |  1
C0006277  |  bronchitis  |  1
C0024623  |  stomach cancer  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:22)
3123  |  HLA-DRB1  |  ORPHANET
4524  |  MTHFR  |  CTD_human
7128  |  TNFAIP3  |  CTD_human
3440  |  IFNA2  |  CTD_human
4615  |  MYD88  |  CTD_human
596  |  BCL2  |  CTD_human;ORPHANET;UNIPROT
1387  |  CREBBP  |  CTD_human
8915  |  BCL10  |  CLINVAR
4548  |  MTR  |  CTD_human
8085  |  KMT2D  |  CTD_human
1879  |  EBF1  |  CTD_human
3492  |  IGH  |  ORPHANET
7298  |  TYMS  |  CTD_human
5820  |  PVT1  |  GWASCAT
2146  |  EZH2  |  CTD_human
8170  |  SLC14A2  |  GWASCAT
942  |  CD86  |  GWASCAT
604  |  BCL6  |  ORPHANET;UNIPROT
57476  |  GRAMD1B  |  GWASCAT
4026  |  LPP  |  GWASCAT
79415  |  C17orf62  |  GWASCAT
2531  |  KDSR  |  CTD_human
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:22)
604  |  BCL6  |  CIPHER
596  |  BCL2  |  CIPHER;CTD_human
958  |  CD40  |  CIPHER
8837  |  CFLAR  |  CIPHER
2212  |  FCGR2A  |  CIPHER
2214  |  FCGR3A  |  CIPHER
2215  |  FCGR3B  |  CIPHER
285834  |  HCG22  |  CIPHER
3119  |  HLA-DQB1  |  CIPHER
4524  |  MTHFR  |  CIPHER;CTD_human
7157  |  TP53  |  CIPHER
7128  |  TNFAIP3  |  CTD_human
4615  |  MYD88  |  CTD_human
1879  |  EBF1  |  CTD_human
8085  |  KMT2D  |  CTD_human
7298  |  TYMS  |  CTD_human
1387  |  CREBBP  |  CTD_human
3440  |  IFNA2  |  CTD_human
100306940  |  FL1  |  CTD_human
2531  |  KDSR  |  CTD_human
2146  |  EZH2  |  CTD_human
4548  |  MTR  |  CTD_human
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:163)
197322  |  ACSF3  |  1.962  |  DISEASES
10840  |  ALDH1L1  |  1.051  |  DISEASES
238  |  ALK  |  2.51  |  DISEASES
257  |  ALX3  |  3.124  |  DISEASES
154810  |  AMOTL1  |  1.725  |  DISEASES
81611  |  ANP32E  |  2.048  |  DISEASES
83478  |  ARHGAP24  |  1.625  |  DISEASES
8289  |  ARID1A  |  2.221  |  DISEASES
537  |  ATP6AP1  |  1.297  |  DISEASES
567  |  B2M  |  3.337  |  DISEASES
53335  |  BCL11A  |  1.352  |  DISEASES
596  |  BCL2  |  2.29  |  DISEASES
10018  |  BCL2L11  |  1.719  |  DISEASES
605  |  BCL7A  |  1.505  |  DISEASES
151888  |  BTLA  |  1.464  |  DISEASES
785  |  CACNB4  |  1.088  |  DISEASES
143384  |  CACUL1  |  2.267  |  DISEASES
84433  |  CARD11  |  1.3  |  DISEASES
833  |  CARS  |  1.299  |  DISEASES
841  |  CASP8  |  1.39  |  DISEASES
896  |  CCND3  |  2.055  |  DISEASES
8812  |  CCNK  |  1.454  |  DISEASES
9332  |  CD163  |  1.775  |  DISEASES
930  |  CD19  |  4.37  |  DISEASES
914  |  CD2  |  1.35  |  DISEASES
29126  |  CD274  |  1.61  |  DISEASES
951  |  CD37  |  1.966  |  DISEASES
958  |  CD40  |  3.344  |  DISEASES
959  |  CD40LG  |  3.378  |  DISEASES
960  |  CD44  |  1.168  |  DISEASES
921  |  CD5  |  5.017  |  DISEASES
1043  |  CD52  |  2.054  |  DISEASES
974  |  CD79B  |  1.898  |  DISEASES
942  |  CD86  |  1.685  |  DISEASES
51755  |  CDK12  |  1.246  |  DISEASES
1018  |  CDK3  |  1.106  |  DISEASES
1029  |  CDKN2A  |  2.665  |  DISEASES
1033  |  CDKN3  |  1.261  |  DISEASES
1378  |  CR1  |  2.87  |  DISEASES
1380  |  CR2  |  4.327  |  DISEASES
9696  |  CROCC  |  2.138  |  DISEASES
9946  |  CRYZL1  |  1.139  |  DISEASES
541466  |  CT45A1  |  1.326  |  DISEASES
6387  |  CXCL12  |  1.343  |  DISEASES
7852  |  CXCR4  |  1.52  |  DISEASES
1612  |  DAPK1  |  1.648  |  DISEASES
81623  |  DEFB126  |  1.921  |  DISEASES
79947  |  DHDDS  |  1.897  |  DISEASES
1791  |  DNTT  |  2.542  |  DISEASES
135656  |  DPCR1  |  1.371  |  DISEASES
1847  |  DUSP5  |  1.899  |  DISEASES
1850  |  DUSP8  |  1.805  |  DISEASES
2045  |  EPHA7  |  3.062  |  DISEASES
3266  |  ERAS  |  1.707  |  DISEASES
355  |  FAS  |  1.695  |  DISEASES
2213  |  FCGR2B  |  2.644  |  DISEASES
2214  |  FCGR3A  |  2.215  |  DISEASES
115350  |  FCRL1  |  1.955  |  DISEASES
84824  |  FCRLA  |  1.306  |  DISEASES
50943  |  FOXP3  |  2.918  |  DISEASES
6624  |  FSCN1  |  1.115  |  DISEASES
8880  |  FUBP1  |  1.053  |  DISEASES
2526  |  FUT4  |  2.152  |  DISEASES
53827  |  FXYD5  |  2.24  |  DISEASES
79695  |  GALNT12  |  2.773  |  DISEASES
257144  |  GCSAM  |  3.974  |  DISEASES
11146  |  GLMN  |  1.145  |  DISEASES
51022  |  GLRX2  |  1.216  |  DISEASES
10672  |  GNA13  |  1.201  |  DISEASES
83873  |  GPR61  |  2.244  |  DISEASES
3055  |  HCK  |  1.354  |  DISEASES
3009  |  HIST1H1B  |  1.084  |  DISEASES
3119  |  HLA-DQB1  |  1.002  |  DISEASES
3120  |  HLA-DQB2  |  1.115  |  DISEASES
388697  |  HRNR  |  2.359  |  DISEASES
219844  |  HYLS1  |  2.502  |  DISEASES
3440  |  IFNA2  |  1.424  |  DISEASES
100423062  |  IGLL5  |  3.317  |  DISEASES
3586  |  IL10  |  1.998  |  DISEASES
3559  |  IL2RA  |  1.579  |  DISEASES
386653  |  IL31  |  1.097  |  DISEASES
3563  |  IL3RA  |  1.55  |  DISEASES
3635  |  INPP5D  |  1.495  |  DISEASES
3662  |  IRF4  |  3.556  |  DISEASES
2531  |  KDSR  |  3.027  |  DISEASES
3805  |  KIR2DL4  |  1.183  |  DISEASES
89857  |  KLHL6  |  1.92  |  DISEASES
55975  |  KLHL7  |  1.343  |  DISEASES
56956  |  LHX9  |  1.736  |  DISEASES
4033  |  LRMP  |  1.468  |  DISEASES
4170  |  MCL1  |  2.688  |  DISEASES
4193  |  MDM2  |  1.11  |  DISEASES
407975  |  MIR17HG  |  1.443  |  DISEASES
4288  |  MKI67  |  1.804  |  DISEASES
4311  |  MME  |  6.11  |  DISEASES
4332  |  MNDA  |  2.969  |  DISEASES
9242  |  MSC  |  2.044  |  DISEASES
4524  |  MTHFR  |  1.3  |  DISEASES
2475  |  MTOR  |  1.876  |  DISEASES
4548  |  MTR  |  1.751  |  DISEASES
4603  |  MYBL1  |  1.018  |  DISEASES
4609  |  MYC  |  4.727  |  DISEASES
4615  |  MYD88  |  1.656  |  DISEASES
9  |  NAT1  |  1.377  |  DISEASES
4751  |  NEK2  |  1.468  |  DISEASES
10360  |  NPM3  |  1.788  |  DISEASES
4306  |  NR3C2  |  3.683  |  DISEASES
145957  |  NRG4  |  1.264  |  DISEASES
286530  |  P2RY8  |  2.15  |  DISEASES
5079  |  PAX5  |  4.162  |  DISEASES
5101  |  PCDH9  |  1.484  |  DISEASES
5111  |  PCNA  |  1.653  |  DISEASES
5133  |  PDCD1  |  2.258  |  DISEASES
80380  |  PDCD1LG2  |  1.384  |  DISEASES
9260  |  PDLIM7  |  1.664  |  DISEASES
5236  |  PGM1  |  1.063  |  DISEASES
5336  |  PLCG2  |  1.136  |  DISEASES
5450  |  POU2AF1  |  2.859  |  DISEASES
5452  |  POU2F2  |  1.466  |  DISEASES
639  |  PRDM1  |  2.765  |  DISEASES
145270  |  PRIMA1  |  4.835  |  DISEASES
5728  |  PTEN  |  1.347  |  DISEASES
5788  |  PTPRC  |  1.961  |  DISEASES
5795  |  PTPRJ  |  2.161  |  DISEASES
166824  |  RASSF6  |  1.479  |  DISEASES
10181  |  RBM5  |  1.088  |  DISEASES
399  |  RHOH  |  3.127  |  DISEASES
6016  |  RIT1  |  2.288  |  DISEASES
55819  |  RNF130  |  1.487  |  DISEASES
4919  |  ROR1  |  1.331  |  DISEASES
64121  |  RRAGC  |  3.411  |  DISEASES
9294  |  S1PR2  |  1.89  |  DISEASES
6304  |  SATB1  |  1.262  |  DISEASES
327657  |  SERPINA9  |  2.007  |  DISEASES
57713  |  SFMBT2  |  2.213  |  DISEASES
6472  |  SHMT2  |  1.622  |  DISEASES
347734  |  SLC35B2  |  4.623  |  DISEASES
23583  |  SMUG1  |  3.946  |  DISEASES
6622  |  SNCA  |  3.611  |  DISEASES
387066  |  SNHG5  |  1.877  |  DISEASES
9021  |  SOCS3  |  1.463  |  DISEASES
6664  |  SOX11  |  3.051  |  DISEASES
6660  |  SOX5  |  1.746  |  DISEASES
6693  |  SPN  |  3.526  |  DISEASES
3925  |  STMN1  |  1.177  |  DISEASES
6850  |  SYK  |  2.468  |  DISEASES
8115  |  TCL1A  |  2.524  |  DISEASES
7027  |  TFDP1  |  1.889  |  DISEASES
7072  |  TIA1  |  1.063  |  DISEASES
7096  |  TLR1  |  1.737  |  DISEASES
54106  |  TLR9  |  1.7  |  DISEASES
51014  |  TMED7  |  2.591  |  DISEASES
57393  |  TMEM27  |  1.122  |  DISEASES
7124  |  TNF  |  1.884  |  DISEASES
7127  |  TNFAIP2  |  1.055  |  DISEASES
8764  |  TNFRSF14  |  3.977  |  DISEASES
8784  |  TNFRSF18  |  1.025  |  DISEASES
3604  |  TNFRSF9  |  1.466  |  DISEASES
10673  |  TNFSF13B  |  2.284  |  DISEASES
706  |  TSPO  |  3.386  |  DISEASES
7716  |  VEZF1  |  1.177  |  DISEASES
7517  |  XRCC3  |  1.122  |  DISEASES
340152  |  ZC3H12D  |  5.554  |  DISEASES
Locus
Symbol | Locus(Total Locus:4)
BCL2  |  18q21.33
IGH  |  14q32.33
BCL6  |  3q27.3
HLA-DRB1  |  6p21.32
Disease ID 85
Disease follicular lymphoma
Integrated Phenotype
HPO | Name(Total Integrated Phenotypes:13)
HP:0002716  |  Lymphadenopathy
HP:0001744  |  Splenomegaly
HP:0002202  |  Pleural effusion
HP:0002665  |  Lymphoma
HP:0012378  |  Fatigue
HP:0100721  |  Mediastinal lymphadenopathy
HP:0030166  |  Night sweats
HP:0001824  |  Weight loss
HP:0001945  |  Fever
HP:0001287  |  Meningitis
HP:0002585  |  Abnormality of the peritoneum
HP:0200036  |  Skin nodule
HP:0001004  |  Lymphedema
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:29)
HP:0002665  |  Lymphoma  |  15
HP:0002664  |  Neoplasia  |  10
HP:0012189  |  Hodgkin disease  |  4
HP:0012191  |  B-cell lymphoma  |  4
HP:0012539  |  Non-Hodgkin lymphoma  |  2
HP:0001735  |  Acute pancreatitis  |  1
HP:0011458  |  Abdominal symptom  |  1
HP:0010784  |  Uterine tumor  |  1
HP:0012126  |  Gastric cancer  |  1
HP:0100242  |  Sarcoma  |  1
HP:0006562  |  Viral hepatitis  |  1
HP:0003002  |  Breast carcinoma  |  1
HP:0001541  |  Ascites  |  1
HP:0002014  |  Diarrhea  |  1
HP:0012223  |  Ruptured spleen  |  1
HP:0004444  |  Spherocytosis  |  1
HP:0001271  |  Polyneuropathy  |  1
HP:0012115  |  Liver inflammation  |  1
HP:0012410  |  Pure red cell aplasia  |  1
HP:0012387  |  Bronchitis  |  1
HP:0004313  |  Decreased immunoglobulin level  |  1
HP:0012570  |  Synovial sarcoma  |  1
HP:0011974  |  Myelofibrosis  |  1
HP:0001289  |  Confusion  |  1
HP:0000763  |  Sensory neuropathy  |  1
HP:0002583  |  Colitis  |  1
HP:0100280  |  Morbus Crohn  |  1
HP:0200034  |  Papule  |  1
HP:0001880  |  Eosinophilia  |  1
Disease ID 85
Disease follicular lymphoma
Manually Symptom
UMLS  | Name(Total Manually Symptoms:12)
C1963234  |  serum sickness
C1536010  |  lymphoma transformation
C1516669  |  clonal evolution
C1112570  |  paraneoplastic pemphigus
C0598766  |  lymphomagenesis
C0392610  |  acquired prothrombin deficiency
C0276652  |  cutaneous aspergillosis
C0033680  |  protein losing enteropathy
C0023524  |  progressive multifocal leukoencephalopathy
C0019618  |  histiocytosis
C0006105  |  brain abscess
C0005699  |  blast crisis
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:1)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:159)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs10484561230256653126HLA-DRB4umls:C0024301BeFreeIn recent genome-wide association studies (GWAS) of FL, several genetic susceptibility loci have been identified on chromosome 6p21.33 (rs6457327) and 6p21.32 (rs10484561, rs2647012) in the human leukocyte antigen class I and class II regions.0.0010857672012NA632697643TG
rs10484561206398813119HLA-DQB1umls:C0024301GAD[Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.]0.0052769482010NA632697643TG
rs1048456122911334266629SEC14L3umls:C0024301BeFreeThe TAP2 SNP was strongly associated with follicular lymphoma (FL, OR = 1.82, 95%CI 1.46-2.26; p = 6.9 × 10(-8)), and was independent of other known loci (rs10484561 and rs2647012) from this region.0.0002714422012NA632697643TG
rs1056503251785865887RAD23Bumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014XRCC4583353158TA,G
rs1056503251785867517XRCC3umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0080012982014XRCC4583353158TA,G
rs1056503251785867518XRCC4umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014XRCC4583353158TA,G
rs1056503251785867486WRNumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0029099162014XRCC4583353158TA,G
rs105650325178586675BRCA2umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014XRCC4583353158TA,G
rs1056503251785864255MGMTumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014XRCC4583353158TA,G
rs1056503251785862067ERCC1umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014XRCC4583353158TA,G
rs11082438252799868170SLC14A2umls:C0024301GWASCATGenome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.0.122014SLC14A21845285245GT
rs11348802225511147673BRAFumls:C0024301BeFreeThe performance of the BRAF V600E-specific VE1 antibody was compared with that of allele-specific polymerase chain reaction (PCR) in 22 formalin-fixed, paraffin-embedded (FFPE) specimens with HCL involvement, along with nine splenic marginal zone lymphomas (SMZLs), 10 follicular lymphomas (FLs), 10 mantle cell lymphomas (MCLs), and 10 chronic lymphocytic leukemia/small lymphocytic lymphomas (CLL/SLLs).0.0002714422015BRAF7140753336AT,G,C
rs12711521230552024155MBPumls:C0024301BeFreeA SNP-based analysis showed that MBP rs8094402 was associated with decreased risks of overall NHL (allele risk OR = 0.72, P-trend = 0.0018), DLBCL (allele risk OR = 0.72, P-trend = 0.036), and FL (allele risk OR = 0.67, P-trend = 0.021), while MASP2 rs12711521 was associated with a decreased risk of DLBCL (allele risk OR = 0.57, P-trend = 0.0042).0.0002714422013MASP2111030859CA
rs127115212305520210747MASP2umls:C0024301BeFreeA SNP-based analysis showed that MBP rs8094402 was associated with decreased risks of overall NHL (allele risk OR = 0.72, P-trend = 0.0018), DLBCL (allele risk OR = 0.72, P-trend = 0.036), and FL (allele risk OR = 0.67, P-trend = 0.021), while MASP2 rs12711521 was associated with a decreased risk of DLBCL (allele risk OR = 0.57, P-trend = 0.0042).0.0002714422013MASP2111030859CA
rs12917251785867517XRCC3umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0080012982014MGMT10129708019CT
rs12917251785867518XRCC4umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014MGMT10129708019CT
rs1291725178586675BRCA2umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014MGMT10129708019CT
rs12917251785862067ERCC1umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014MGMT10129708019CT
rs12917224304434255MGMTumls:C0024301BeFreeAfter stratification by major NHL histological subtypes, MGMT (rs12917) modified the association between chlorinated solvents and the risk of diffuse large B-cell lymphoma (Pfor interaction=0.0027) and follicular lymphoma (Pfor interaction=0.0024).0.0031813582012MGMT10129708019CT
rs12917251785867486WRNumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0029099162014MGMT10129708019CT
rs12917251785865887RAD23Bumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014MGMT10129708019CT
rs12917251785864255MGMTumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014MGMT10129708019CT
rs1325499025279986596BCL2umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.3438045162014PVT18128064205CT
rs13254990252799864026LPPumls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014PVT18128064205CT
rs13254990252799865820PVT1umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014PVT18128064205CT
rs13254990252799865820PVT1umls:C0024301GWASCATFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014PVT18128064205CT
rs13254990252799862113ETS1umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.0002714422014PVT18128064205CT
rs1325499025279986643CXCR5umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.0008143262014PVT18128064205CT
rs1346044251785867486WRNumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0029099162014WRN;LOC105379359831167138TC
rs1346044251785862067ERCC1umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014WRN;LOC105379359831167138TC
rs134604425178586675BRCA2umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014WRN;LOC105379359831167138TC
rs1346044251785867517XRCC3umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0080012982014WRN;LOC105379359831167138TC
rs1346044251785864255MGMTumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014WRN;LOC105379359831167138TC
rs1346044251785865887RAD23Bumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014WRN;LOC105379359831167138TC
rs1346044251785867518XRCC4umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014WRN;LOC105379359831167138TC
rs14484825178586675BRCA2umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014BRCA21332332592AC
rs14484821476145675BRCA2umls:C0024301BeFreeAssociation of follicular lymphoma risk with BRCA2 N372H polymorphism in Slovak population.0.0031813582012BRCA21332332592AC
rs144848214761453981LIG4umls:C0024301BeFreeWe have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls.0.0026384742012BRCA21332332592AC
rs144848251785867518XRCC4umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014BRCA21332332592AC
rs144848214761455896RAG1umls:C0024301BeFreeWe have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls.0.0026384742012BRCA21332332592AC
rs144848251785862067ERCC1umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014BRCA21332332592AC
rs144848251785867486WRNumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0029099162014BRCA21332332592AC
rs144848251785865887RAD23Bumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014BRCA21332332592AC
rs144848214761457486WRNumls:C0024301BeFreeWe have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls.0.0029099162012BRCA21332332592AC
rs144848251785864255MGMTumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014BRCA21332332592AC
rs144848251785867517XRCC3umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0080012982014BRCA21332332592AC
rs1494555209526897124TNFumls:C0024301BeFreeAfter stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma.0.0069055992011IL7R535871088GA
rs1695174546002950GSTP1umls:C0024301BeFreeWe studied deletions of GSTM1 and GSTT1, and the GSTP1 Ile(105)Val polymorphism in 89 patients with follicular lymphoma (FL).0.0052769482007GSTP11167585218AG
rs17749561252799865820PVT1umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014NA1863115978GA
rs1774956125279986643CXCR5umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.0008143262014NA1863115978GA
rs1774956125279986596BCL2umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.3438045162014NA1863115978GA
rs17749561252799862113ETS1umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.0002714422014NA1863115978GA
rs17749561252799864026LPPumls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014NA1863115978GA
rs1805329251785864255MGMTumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014RAD23B9107322047CT
rs1805329251785865887RAD23Bumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014RAD23B9107322047CT
rs1805329251785867486WRNumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0029099162014RAD23B9107322047CT
rs1805329251785867517XRCC3umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0080012982014RAD23B9107322047CT
rs180532925178586675BRCA2umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014RAD23B9107322047CT
rs1805329251785862067ERCC1umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014RAD23B9107322047CT
rs1805329251785867518XRCC4umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014RAD23B9107322047CT
rs180537725178586675BRCA2umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014XRCC4583353124GA
rs1805377251785867518XRCC4umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014XRCC4583353124GA
rs1805377251785864255MGMTumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014XRCC4583353124GA
rs1805377251785865887RAD23Bumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014XRCC4583353124GA
rs1805377251785867486WRNumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0029099162014XRCC4583353124GA
rs1805377251785867517XRCC3umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0080012982014XRCC4583353124GA
rs1805377251785862067ERCC1umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014XRCC4583353124GA
rs188383220473910958CD40umls:C0024301BeFreeData from earlier studies that are part of this pooling study implicate a functional polymorphism (-1C>T, rs1883832) in the TNFRSF5 gene encoding CD40 in the etiology of follicular lymphoma.0.00890152011CD402046118343TC
rs20541209526897124TNFumls:C0024301BeFreeAfter stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma.0.0069055992011IL135132660272AG
rs2227973214761457486WRNumls:C0024301BeFreeWe have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls.0.0029099162012RAG11136575763AG
rs2227973214761453981LIG4umls:C0024301BeFreeWe have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls.0.0026384742012RAG11136575763AG
rs2227973214761455896RAG1umls:C0024301BeFreeWe have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls.0.0026384742012RAG11136575763AG
rs2230009214761453981LIG4umls:C0024301BeFreeWe have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls.0.0026384742012WRN831064419GA
rs2230009214761457486WRNumls:C0024301BeFreeWe have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls.0.0029099162012WRN831064419GA
rs2230009214761455896RAG1umls:C0024301BeFreeWe have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls.0.0026384742012WRN831064419GA
rs2308321251785867486WRNumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0029099162014MGMT;LOC10537855910129766800AG
rs2308321251785862067ERCC1umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014MGMT;LOC10537855910129766800AG
rs2308321251785867518XRCC4umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014MGMT;LOC10537855910129766800AG
rs2308321251785864255MGMTumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014MGMT;LOC10537855910129766800AG
rs2308321251785865887RAD23Bumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014MGMT;LOC10537855910129766800AG
rs230832125178586675BRCA2umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014MGMT;LOC10537855910129766800AG
rs2308321251785867517XRCC3umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0080012982014MGMT;LOC10537855910129766800AG
rs2308327251785865887RAD23Bumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014MGMT;LOC10537855910129766906AG
rs2308327251785867486WRNumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0029099162014MGMT;LOC10537855910129766906AG
rs2308327251785867518XRCC4umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014MGMT;LOC10537855910129766906AG
rs2308327251785864255MGMTumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014MGMT;LOC10537855910129766906AG
rs2308327251785867517XRCC3umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0080012982014MGMT;LOC10537855910129766906AG
rs2308327251785862067ERCC1umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014MGMT;LOC10537855910129766906AG
rs230832725178586675BRCA2umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014MGMT;LOC10537855910129766906AG
rs2647012230256653126HLA-DRB4umls:C0024301BeFreeIn recent genome-wide association studies (GWAS) of FL, several genetic susceptibility loci have been identified on chromosome 6p21.33 (rs6457327) and 6p21.32 (rs10484561, rs2647012) in the human leukocyte antigen class I and class II regions.0.0010857672012NA632696681TC
rs264701224304973129831RBM45umls:C0024301BeFreeWe confirmed that FL-protective rs2647012-linked variants, in high linkage disequilibrium with the extended haplotype DRB1*15:01-DQA1*01:02-DQB1*06:02, correlate with increased HLA-DQB1 expression.0.0008143262013NA632696681TC
rs264701222296171129831RBM45umls:C0024301BeFreeMoreover, DRB1*15-DQA1*01-DQB1*06 was highly correlated with an established FL risk locus, rs2647012.0.0008143262012NA632696681TC
rs264701222911334266629SEC14L3umls:C0024301BeFreeThe TAP2 SNP was strongly associated with follicular lymphoma (FL, OR = 1.82, 95%CI 1.46-2.26; p = 6.9 × 10(-8)), and was independent of other known loci (rs10484561 and rs2647012) from this region.0.0002714422012NA632696681TC
rs2647012215330743119HLA-DQB1umls:C0024301GAD[GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma.]0.0052769482011NA632696681TC
rs268141625279986942CD86umls:C0024301GWASCATGenome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.0.122014CD863122098766GA
rs2855429211487566015RING1umls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011COL11A2633190412AC
rs2855429211487566257RXRBumls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011COL11A2633190412AC
rs285542921148756199AIF1umls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011COL11A2633190412AC
rs2855429211487567918GPANK1umls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011COL11A2633190412AC
rs285759721148756199AIF1umls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011AIF1631617223TA
rs2857597211487566257RXRBumls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011AIF1631617223TA
rs2857597211487566015RING1umls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011AIF1631617223TA
rs2857597211487567918GPANK1umls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011AIF1631617223TA
rs3020314186361242099ESR1umls:C0024301BeFreeFour ESR1 SNPs were associated with follicular lymphoma (FL) in the U.S. study, with rs3020314 remaining associated with reduced risk of FL after multiple testing adjustments [odds ratio (OR) = 0.42, 95% confidence interval (CI) = 0.23-0.77) and replication in the German study (OR = 0.24, 95% CI = 0.06-0.94).0.0002714422008ESR16151949537CT
rs3115667211487566257RXRBumls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011NA631675622TC
rs311566721148756199AIF1umls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011NA631675622TC
rs3115667211487567918GPANK1umls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011NA631675622TC
rs3115667211487566015RING1umls:C0024301BeFreeAccordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05).0.0002714422011NA631675622TC
rs3212961251785867517XRCC3umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0080012982014ERCC11945419065GT,A
rs3212961251785862067ERCC1umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014ERCC11945419065GT,A
rs3212961251785867486WRNumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0029099162014ERCC11945419065GT,A
rs3212961251785865887RAD23Bumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014ERCC11945419065GT,A
rs3212961251785867518XRCC4umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014ERCC11945419065GT,A
rs3212961251785864255MGMTumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014ERCC11945419065GT,A
rs321296125178586675BRCA2umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014ERCC11945419065GT,A
rs37519132527998679415C17orf62umls:C0024301GWASCATGenome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.0.122014C17orf621782447676TC
rs37890681933655210018BCL2L11umls:C0024301BeFreeVariants in BCL2L11 were strongly related to follicular lymphoma only, particularly rs3789068 (OR(AG), 1.41; 95% CI, 1.10-1.81; OR(GG), 1.65; 95% CI, 1.25-2.19; P(trend) = 0.0004).0.0026384742009BCL2L112111151670AG
rs464595980129554609MYCumls:C0024301BeFreeAn unusual asparagine to serine mutation at codon 11 was identified in several transformed follicular lymphomas without MYC rearrangement but not in normal tissues from patients with this mutation.0.0075244281994MYC8127738294AC,G
rs4937362252799865820PVT1umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014LOC10536956811128622844TC
rs493736225279986643CXCR5umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.0008143262014LOC10536956811128622844TC
rs4937362252799862113ETS1umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.0002714422014LOC10536956811128622844TC
rs4937362252799864026LPPumls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014LOC10536956811128622844TC
rs493736225279986596BCL2umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.3438045162014LOC10536956811128622844TC
rs4938573252799862113ETS1umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.0002714422014NA11118871133CT
rs4938573252799864026LPPumls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014NA11118871133CT
rs493857325279986643CXCR5umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.0008143262014NA11118871133CT
rs493857325279986596BCL2umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.3438045162014NA11118871133CT
rs4938573252799865820PVT1umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014NA11118871133CT
rs568408209526897124TNFumls:C0024301BeFreeAfter stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma.0.0069055992011IL12A;IL12A-AS13159995680GA
rs587776632NA8915BCL10umls:C0024301CLINVARNA0.122909916NABCL10185267902-AA
rs587776633NA8915BCL10umls:C0024301CLINVARNA0.122909916NABCL10185270733-T
rs587776634NA8915BCL10umls:C0024301CLINVARNA0.122909916NABCL10185267788TGCCTACTTCTAGAACA-
rs587776635NA8915BCL10umls:C0024301CLINVARNA0.122909916NABCL10185267919T-
rs587776636NA8915BCL10umls:C0024301CLINVARNA0.122909916NABCL10185267931-A
rs587776637NA8915BCL10umls:C0024301CLINVARNA0.122909916NABCL10185267692CTT-
rs601341171698014361MRE11Aumls:C0024301BeFreeA protective effect against follicular lymphoma was seen for the MRE11 rs601341 variant, the homozygous T allele being associated with an odds ratio (OR) of 0.50, 95% confidence interval (95% CI) 0.26 - 0.97, while a protective effect was seen for the MRE11 haplotype GCTCA (OR 0.72, 95% CI 0.53 - 0.97) for diffuse large B-cell lymphoma.0.0002714422006MRE11A1194434611GA
rs60547062305520281623DEFB126umls:C0024301BeFreeWe also observed an increased risk of FL for DEFB126 rs6054706 (allele risk OR = 1.39, P-trend = 0.033).0.0002714422013NA20149223CT
rs644430525279986643CXCR5umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.0008143262014LPP3188582114GA
rs6444305252799862113ETS1umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.0002714422014LPP3188582114GA
rs6444305252799865820PVT1umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014LPP3188582114GA
rs6444305252799864026LPPumls:C0024301GWASCATFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014LPP3188582114GA
rs6444305252799864026LPPumls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.1202714422014LPP3188582114GA
rs644430525279986596BCL2umls:C0024301BeFreeFive non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1.0.3438045162014LPP3188582114GA
rs6457327230256653126HLA-DRB4umls:C0024301BeFreeIn recent genome-wide association studies (GWAS) of FL, several genetic susceptibility loci have been identified on chromosome 6p21.33 (rs6457327) and 6p21.32 (rs10484561, rs2647012) in the human leukocyte antigen class I and class II regions.0.0010857672012NA631106253AC
rs645732720639881285834HCG22umls:C0024301GAD[Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.]0.0047340642010NA631106253AC
rs645732719620980285834HCG22umls:C0024301GAD[Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma.]0.0047340642009NA631106253AC
rs7356652063988179827CLMPumls:C0024301GAD[Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.]0.0023670322010GRAMD1B11123490689GA
rs7356652063988157476GRAMD1Bumls:C0024301GWASCATGenome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.0.122010GRAMD1B11123490689GA
rs737865162149221312COMTumls:C0024301BeFreeORs for all non-Hodgkin lymphoma and follicular lymphoma among women were decreased for COMT IVS1 701A>G [rs737865; variant allele: OR, 0.53; 95% CI, 0.34-0.82; OR, 0.42; 95% CI, 0.23-0.78, respectively].0.0002714422005COMT;TXNRD22219942598AG
rs8094402230552024155MBPumls:C0024301BeFreeA SNP-based analysis showed that MBP rs8094402 was associated with decreased risks of overall NHL (allele risk OR = 0.72, P-trend = 0.0018), DLBCL (allele risk OR = 0.72, P-trend = 0.036), and FL (allele risk OR = 0.67, P-trend = 0.021), while MASP2 rs12711521 was associated with a decreased risk of DLBCL (allele risk OR = 0.57, P-trend = 0.0042).0.0002714422013MBP1876995493AG
rs80944022305520210747MASP2umls:C0024301BeFreeA SNP-based analysis showed that MBP rs8094402 was associated with decreased risks of overall NHL (allele risk OR = 0.72, P-trend = 0.0018), DLBCL (allele risk OR = 0.72, P-trend = 0.036), and FL (allele risk OR = 0.67, P-trend = 0.021), while MASP2 rs12711521 was associated with a decreased risk of DLBCL (allele risk OR = 0.57, P-trend = 0.0042).0.0002714422013MBP1876995493AG
rs861539251785867486WRNumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0029099162014KLC1;XRCC314103699416GA
rs86153925178586675BRCA2umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014KLC1;XRCC314103699416GA
rs861539251785864255MGMTumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0031813582014KLC1;XRCC314103699416GA
rs861539251785867517XRCC3umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0080012982014KLC1;XRCC314103699416GA
rs861539251785867518XRCC4umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014KLC1;XRCC314103699416GA
rs861539251785862067ERCC1umls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014KLC1;XRCC314103699416GA
rs861539251785865887RAD23Bumls:C0024301BeFreeThe following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively].0.0026384742014KLC1;XRCC314103699416GA
rs9808753209526897124TNFumls:C0024301BeFreeAfter stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma.0.0069055992011IFNGR22133415005AG
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:2)
HP ID HP Name MP ID MP Name Annotation
HP:0002585Abnormality of the peritoneumMP:0004500increased incidence of tumors by ionizing radiation inductionhigher than normal frequency of tumor incidence induced by radiation in which the individual particle or photon carries sufficient energy to completely remove an electron from its orbit; common types of this radiation include gamma-rays and X-rays
HP:0001824Weight lossMP:0005114premature hair lossrelease of fur at an earlier than expected time
Mapped by homologous gene(Total Items:12)
HP ID HP Name MP ID MP Name Annotation
HP:0001945FeverMP:0020254decreased collagen leveldecreased level of the main structural protein of the various connective tissues in animals
HP:0001824Weight lossMP:0020220decreased tear productiondecreased production of the amount of fluid produced in the eye
HP:0002202Pleural effusionMP:0014233bile duct epithelium hyperplasia
HP:0100721Mediastinal lymphadenopathyMP:0014169decreased brown adipose tissue massdecreased physical bulk or volume of brown adipose tissue
HP:0200036Skin noduleMP:0013601increased testis apoptosisincrease in the number of cells of the male reproductive glands undergoing programmed cell death
HP:0001287MeningitisMP:0020215impaired blood coagulationimpaired ability of the blood to clot
HP:0002585Abnormality of the peritoneumMP:0014126increased mammary gland apoptosisincrease in the number of any cells of a mammary gland undergoing programmed cell death
HP:0002716LymphadenopathyMP:0020215impaired blood coagulationimpaired ability of the blood to clot
HP:0002665LymphomaMP:0020154impaired humoral immune responseimpaired response of the immune system that mediates secreted antibodies produced in B cells
HP:0001004LymphedemaMP:0014171increased fatty acid oxidationincreased rate or incidence of the process of removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydr
HP:0012378FatigueMP:0013659abnormal erythroid lineage cell morphologyany structural anomaly of an immature or mature cell in the lineage leading to and including erythrocytes
HP:0001744SplenomegalyMP:0020254decreased collagen leveldecreased level of the main structural protein of the various connective tissues in animals
Disease ID 85
Disease follicular lymphoma
Case(Waiting for update.)