follicular lymphoma |
Disease ID | 85 |
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Disease | follicular lymphoma |
Definition | Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the LYMPH NODES. The nodules resemble to some extent the GERMINAL CENTER of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center B-LYMPHOCYTES. |
Synonym | (nodular lymphoma: brill-symmers disease) or (reticulosarcoma - follicular or nodular) (nodular lymphoma: brill-symmers disease) or (reticulosarcoma - follicular or nodular) (disorder) [m]brill - symmers' disease [m]follicular lymphosarcoma nos [m]giant follicular lymphoma [m]malignant lymphoma, centroblastic-centrocytic, follicular [m]malignant lymphoma, centroblastic-centrocytic, follicular (morphologic abnormality) [m]malignant lymphoma, nodular nos [m]malignant lymphoma, nodular nos (& [brill - symmers' disease]) [m]malignant lymphoma, nodular nos (& [brill - symmers' disease]) (disorder) [m]malignant lymphoma, nodular nos (morphologic abnormality) [m]nodular lymphosarcoma nos brill - symmers' disease brill symmers dis brill symmers disease brill-symmers disease disease, brill-symmers follic lymphoma follic lymphoma giant follicle center lymphoma follicular centre cell lymphoma follicular low grade b-cell lymphoma follicular low grade b-cell lymphoma (disorder) follicular lymphoma (morphologic abnormality) follicular lymphoma nos follicular lymphoma, giant follicular lymphoma: [non-hodgkin's] or [nos] follicular lymphoma: [non-hodgkin's] or [nos] (disorder) follicular lymphomas follicular lymphomas, giant follicular lymphosarcoma follicular non-hodgkin lymphoma follicular non-hodgkin's lymphoma follicular non-hodgkin's lymphoma (disorder) germinoblastoma, follicular giant follic lymphoma giant follicular lymphoma giant follicular lymphomas giant follicular lymphosarcoma lymphoma follic lymphoma follicular lymphoma giant follic lymphoma, follicular lymphoma, follicular [disease/finding] lymphoma, follicular centre cell lymphoma, follicular, malignant lymphoma, giant follicular lymphoma, nodular lymphomas, follicular lymphomas, giant follicular lymphomas, nodular lymphosarcoma follicular malignant lymphoma, centroblastic-centrocytic, follicular malignant lymphoma, centroblastic-centrocytic, follicular (disorder) malignant lymphoma, centroblastic-centrocytic, follicular (morphologic abnormality) malignant lymphoma, centroblastic-centrocytic, follicular -retired- malignant lymphoma, follicle center malignant lymphoma, follicle center, follicular malignant lymphoma, follicle centre malignant lymphoma, follicle centre, follicular malignant lymphoma, follicular malignant lymphoma, follicular, nos malignant lymphoma, lymphocytic, nodular malignant lymphoma, lymphocytic, nodular, nos malignant lymphoma, nodular malignant lymphoma, nodular, nos nodular lymphocytic lymphoma nodular lymphoma nodular lymphoma (brill - symmers disease) nodular lymphoma (disorder) nodular lymphoma nos nodular lymphoma nos (disorder) nodular lymphoma of unspecified site nodular lymphoma of unspecified site (disorder) nodular lymphomas nodular lymphosarcoma nodular malignant lymphoma reticulosarcoma - follicular or nodular |
Orphanet | |
DOID | |
UMLS | C0024301 |
MeSH | |
SNOMED-CT | |
Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:47) C0024299 | lymphoma | 15 C0024299 | lymphomas | 7 C0079731 | b-cell lymphoma | 4 C0334634 | mantle cell lymphoma | 2 C0079744 | diffuse large b-cell lymphoma | 2 C0019829 | hodgkin lymphoma | 2 C0030807 | pemphigus | 2 C0079731 | b-cell lymphomas | 2 C0024305 | non-hodgkin lymphoma | 2 C0019829 | hodgkin's lymphoma | 2 C0042345 | varices | 1 C0039101 | synovial sarcoma | 1 C0011991 | diarrhea | 1 C0002173 | follicular mucinosis | 1 C0001418 | adenocarcinoma | 1 C1704214 | xanthogranuloma | 1 C0041234 | chagas disease | 1 C0040053 | thrombus | 1 C0010346 | crohn's disease | 1 C0442874 | neuropathy | 1 C0037753 | sparganosis | 1 C0151313 | sensory neuropathy | 1 C0019163 | viral hepatitis b | 1 C0949272 | ileocolitis | 1 C0472817 | whim syndrome | 1 C0152025 | polyneuropathy | 1 C0042721 | viral hepatitis | 1 C0019158 | hepatitis | 1 C0034902 | pure red cell aplasia | 1 C0281963 | red cell aplasia | 1 C0024301 | follicular non-hodgkin's lymphoma | 1 C0043324 | juvenile xanthogranuloma | 1 C0006142 | breast cancer | 1 C0007104 | carcinoma of the breast | 1 C0037889 | hereditary spherocytosis | 1 C0024623 | gastric cancer | 1 C0079731 | b-cell non-hodgkin lymphoma | 1 C0001339 | acute pancreatitis | 1 C0019163 | hepatitis b | 1 C1134719 | invasive ductal carcinoma of the breast | 1 C0341335 | cmv colitis | 1 C1261473 | sarcoma | 1 C0079734 | diffuse lymphoma | 1 C0009319 | colitis | 1 C0024305 | non-hodgkin's lymphoma | 1 C0006277 | bronchitis | 1 C0024623 | stomach cancer | 1 |
Curated Gene | Entrez_id | Symbol | Resource(Total Genes:22) 3123 | HLA-DRB1 | ORPHANET 4524 | MTHFR | CTD_human 7128 | TNFAIP3 | CTD_human 3440 | IFNA2 | CTD_human 4615 | MYD88 | CTD_human 596 | BCL2 | CTD_human;ORPHANET;UNIPROT 1387 | CREBBP | CTD_human 8915 | BCL10 | CLINVAR 4548 | MTR | CTD_human 8085 | KMT2D | CTD_human 1879 | EBF1 | CTD_human 3492 | IGH | ORPHANET 7298 | TYMS | CTD_human 5820 | PVT1 | GWASCAT 2146 | EZH2 | CTD_human 8170 | SLC14A2 | GWASCAT 942 | CD86 | GWASCAT 604 | BCL6 | ORPHANET;UNIPROT 57476 | GRAMD1B | GWASCAT 4026 | LPP | GWASCAT 79415 | C17orf62 | GWASCAT 2531 | KDSR | CTD_human |
Inferring Gene | Entrez_id | Symbol | Resource(Total Genes:22) 604 | BCL6 | CIPHER 596 | BCL2 | CIPHER;CTD_human 958 | CD40 | CIPHER 8837 | CFLAR | CIPHER 2212 | FCGR2A | CIPHER 2214 | FCGR3A | CIPHER 2215 | FCGR3B | CIPHER 285834 | HCG22 | CIPHER 3119 | HLA-DQB1 | CIPHER 4524 | MTHFR | CIPHER;CTD_human 7157 | TP53 | CIPHER 7128 | TNFAIP3 | CTD_human 4615 | MYD88 | CTD_human 1879 | EBF1 | CTD_human 8085 | KMT2D | CTD_human 7298 | TYMS | CTD_human 1387 | CREBBP | CTD_human 3440 | IFNA2 | CTD_human 100306940 | FL1 | CTD_human 2531 | KDSR | CTD_human 2146 | EZH2 | CTD_human 4548 | MTR | CTD_human |
Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:163) 197322 | ACSF3 | 1.962 | DISEASES 10840 | ALDH1L1 | 1.051 | DISEASES 238 | ALK | 2.51 | DISEASES 257 | ALX3 | 3.124 | DISEASES 154810 | AMOTL1 | 1.725 | DISEASES 81611 | ANP32E | 2.048 | DISEASES 83478 | ARHGAP24 | 1.625 | DISEASES 8289 | ARID1A | 2.221 | DISEASES 537 | ATP6AP1 | 1.297 | DISEASES 567 | B2M | 3.337 | DISEASES 53335 | BCL11A | 1.352 | DISEASES 596 | BCL2 | 2.29 | DISEASES 10018 | BCL2L11 | 1.719 | DISEASES 605 | BCL7A | 1.505 | DISEASES 151888 | BTLA | 1.464 | DISEASES 785 | CACNB4 | 1.088 | DISEASES 143384 | CACUL1 | 2.267 | DISEASES 84433 | CARD11 | 1.3 | DISEASES 833 | CARS | 1.299 | DISEASES 841 | CASP8 | 1.39 | DISEASES 896 | CCND3 | 2.055 | DISEASES 8812 | CCNK | 1.454 | DISEASES 9332 | CD163 | 1.775 | DISEASES 930 | CD19 | 4.37 | DISEASES 914 | CD2 | 1.35 | DISEASES 29126 | CD274 | 1.61 | DISEASES 951 | CD37 | 1.966 | DISEASES 958 | CD40 | 3.344 | DISEASES 959 | CD40LG | 3.378 | DISEASES 960 | CD44 | 1.168 | DISEASES 921 | CD5 | 5.017 | DISEASES 1043 | CD52 | 2.054 | DISEASES 974 | CD79B | 1.898 | DISEASES 942 | CD86 | 1.685 | DISEASES 51755 | CDK12 | 1.246 | DISEASES 1018 | CDK3 | 1.106 | DISEASES 1029 | CDKN2A | 2.665 | DISEASES 1033 | CDKN3 | 1.261 | DISEASES 1378 | CR1 | 2.87 | DISEASES 1380 | CR2 | 4.327 | DISEASES 9696 | CROCC | 2.138 | DISEASES 9946 | CRYZL1 | 1.139 | DISEASES 541466 | CT45A1 | 1.326 | DISEASES 6387 | CXCL12 | 1.343 | DISEASES 7852 | CXCR4 | 1.52 | DISEASES 1612 | DAPK1 | 1.648 | DISEASES 81623 | DEFB126 | 1.921 | DISEASES 79947 | DHDDS | 1.897 | DISEASES 1791 | DNTT | 2.542 | DISEASES 135656 | DPCR1 | 1.371 | DISEASES 1847 | DUSP5 | 1.899 | DISEASES 1850 | DUSP8 | 1.805 | DISEASES 2045 | EPHA7 | 3.062 | DISEASES 3266 | ERAS | 1.707 | DISEASES 355 | FAS | 1.695 | DISEASES 2213 | FCGR2B | 2.644 | DISEASES 2214 | FCGR3A | 2.215 | DISEASES 115350 | FCRL1 | 1.955 | DISEASES 84824 | FCRLA | 1.306 | DISEASES 50943 | FOXP3 | 2.918 | DISEASES 6624 | FSCN1 | 1.115 | DISEASES 8880 | FUBP1 | 1.053 | DISEASES 2526 | FUT4 | 2.152 | DISEASES 53827 | FXYD5 | 2.24 | DISEASES 79695 | GALNT12 | 2.773 | DISEASES 257144 | GCSAM | 3.974 | DISEASES 11146 | GLMN | 1.145 | DISEASES 51022 | GLRX2 | 1.216 | DISEASES 10672 | GNA13 | 1.201 | DISEASES 83873 | GPR61 | 2.244 | DISEASES 3055 | HCK | 1.354 | DISEASES 3009 | HIST1H1B | 1.084 | DISEASES 3119 | HLA-DQB1 | 1.002 | DISEASES 3120 | HLA-DQB2 | 1.115 | DISEASES 388697 | HRNR | 2.359 | DISEASES 219844 | HYLS1 | 2.502 | DISEASES 3440 | IFNA2 | 1.424 | DISEASES 100423062 | IGLL5 | 3.317 | DISEASES 3586 | IL10 | 1.998 | DISEASES 3559 | IL2RA | 1.579 | DISEASES 386653 | IL31 | 1.097 | DISEASES 3563 | IL3RA | 1.55 | DISEASES 3635 | INPP5D | 1.495 | DISEASES 3662 | IRF4 | 3.556 | DISEASES 2531 | KDSR | 3.027 | DISEASES 3805 | KIR2DL4 | 1.183 | DISEASES 89857 | KLHL6 | 1.92 | DISEASES 55975 | KLHL7 | 1.343 | DISEASES 56956 | LHX9 | 1.736 | DISEASES 4033 | LRMP | 1.468 | DISEASES 4170 | MCL1 | 2.688 | DISEASES 4193 | MDM2 | 1.11 | DISEASES 407975 | MIR17HG | 1.443 | DISEASES 4288 | MKI67 | 1.804 | DISEASES 4311 | MME | 6.11 | DISEASES 4332 | MNDA | 2.969 | DISEASES 9242 | MSC | 2.044 | DISEASES 4524 | MTHFR | 1.3 | DISEASES 2475 | MTOR | 1.876 | DISEASES 4548 | MTR | 1.751 | DISEASES 4603 | MYBL1 | 1.018 | DISEASES 4609 | MYC | 4.727 | DISEASES 4615 | MYD88 | 1.656 | DISEASES 9 | NAT1 | 1.377 | DISEASES 4751 | NEK2 | 1.468 | DISEASES 10360 | NPM3 | 1.788 | DISEASES 4306 | NR3C2 | 3.683 | DISEASES 145957 | NRG4 | 1.264 | DISEASES 286530 | P2RY8 | 2.15 | DISEASES 5079 | PAX5 | 4.162 | DISEASES 5101 | PCDH9 | 1.484 | DISEASES 5111 | PCNA | 1.653 | DISEASES 5133 | PDCD1 | 2.258 | DISEASES 80380 | PDCD1LG2 | 1.384 | DISEASES 9260 | PDLIM7 | 1.664 | DISEASES 5236 | PGM1 | 1.063 | DISEASES 5336 | PLCG2 | 1.136 | DISEASES 5450 | POU2AF1 | 2.859 | DISEASES 5452 | POU2F2 | 1.466 | DISEASES 639 | PRDM1 | 2.765 | DISEASES 145270 | PRIMA1 | 4.835 | DISEASES 5728 | PTEN | 1.347 | DISEASES 5788 | PTPRC | 1.961 | DISEASES 5795 | PTPRJ | 2.161 | DISEASES 166824 | RASSF6 | 1.479 | DISEASES 10181 | RBM5 | 1.088 | DISEASES 399 | RHOH | 3.127 | DISEASES 6016 | RIT1 | 2.288 | DISEASES 55819 | RNF130 | 1.487 | DISEASES 4919 | ROR1 | 1.331 | DISEASES 64121 | RRAGC | 3.411 | DISEASES 9294 | S1PR2 | 1.89 | DISEASES 6304 | SATB1 | 1.262 | DISEASES 327657 | SERPINA9 | 2.007 | DISEASES 57713 | SFMBT2 | 2.213 | DISEASES 6472 | SHMT2 | 1.622 | DISEASES 347734 | SLC35B2 | 4.623 | DISEASES 23583 | SMUG1 | 3.946 | DISEASES 6622 | SNCA | 3.611 | DISEASES 387066 | SNHG5 | 1.877 | DISEASES 9021 | SOCS3 | 1.463 | DISEASES 6664 | SOX11 | 3.051 | DISEASES 6660 | SOX5 | 1.746 | DISEASES 6693 | SPN | 3.526 | DISEASES 3925 | STMN1 | 1.177 | DISEASES 6850 | SYK | 2.468 | DISEASES 8115 | TCL1A | 2.524 | DISEASES 7027 | TFDP1 | 1.889 | DISEASES 7072 | TIA1 | 1.063 | DISEASES 7096 | TLR1 | 1.737 | DISEASES 54106 | TLR9 | 1.7 | DISEASES 51014 | TMED7 | 2.591 | DISEASES 57393 | TMEM27 | 1.122 | DISEASES 7124 | TNF | 1.884 | DISEASES 7127 | TNFAIP2 | 1.055 | DISEASES 8764 | TNFRSF14 | 3.977 | DISEASES 8784 | TNFRSF18 | 1.025 | DISEASES 3604 | TNFRSF9 | 1.466 | DISEASES 10673 | TNFSF13B | 2.284 | DISEASES 706 | TSPO | 3.386 | DISEASES 7716 | VEZF1 | 1.177 | DISEASES 7517 | XRCC3 | 1.122 | DISEASES 340152 | ZC3H12D | 5.554 | DISEASES |
Locus | Symbol | Locus(Total Locus:4) |
Disease ID | 85 |
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Disease | follicular lymphoma |
Manually Symptom | UMLS | Name(Total Manually Symptoms:12) C1963234 | serum sickness C1536010 | lymphoma transformation C1516669 | clonal evolution C1112570 | paraneoplastic pemphigus C0598766 | lymphomagenesis C0392610 | acquired prothrombin deficiency C0276652 | cutaneous aspergillosis C0033680 | protein losing enteropathy C0023524 | progressive multifocal leukoencephalopathy C0019618 | histiocytosis C0006105 | brain abscess C0005699 | blast crisis |
Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
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(Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
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(Waiting for update.) |
All Snps(Total Genotypes:159) | |||||||||||||
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snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
rs10484561 | 23025665 | 3126 | HLA-DRB4 | umls:C0024301 | BeFree | In recent genome-wide association studies (GWAS) of FL, several genetic susceptibility loci have been identified on chromosome 6p21.33 (rs6457327) and 6p21.32 (rs10484561, rs2647012) in the human leukocyte antigen class I and class II regions. | 0.001085767 | 2012 | NA | 6 | 32697643 | T | G |
rs10484561 | 20639881 | 3119 | HLA-DQB1 | umls:C0024301 | GAD | [Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.] | 0.005276948 | 2010 | NA | 6 | 32697643 | T | G |
rs10484561 | 22911334 | 266629 | SEC14L3 | umls:C0024301 | BeFree | The TAP2 SNP was strongly associated with follicular lymphoma (FL, OR = 1.82, 95%CI 1.46-2.26; p = 6.9 × 10(-8)), and was independent of other known loci (rs10484561 and rs2647012) from this region. | 0.000271442 | 2012 | NA | 6 | 32697643 | T | G |
rs1056503 | 25178586 | 5887 | RAD23B | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | XRCC4 | 5 | 83353158 | T | A,G |
rs1056503 | 25178586 | 7517 | XRCC3 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.008001298 | 2014 | XRCC4 | 5 | 83353158 | T | A,G |
rs1056503 | 25178586 | 7518 | XRCC4 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | XRCC4 | 5 | 83353158 | T | A,G |
rs1056503 | 25178586 | 7486 | WRN | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002909916 | 2014 | XRCC4 | 5 | 83353158 | T | A,G |
rs1056503 | 25178586 | 675 | BRCA2 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | XRCC4 | 5 | 83353158 | T | A,G |
rs1056503 | 25178586 | 4255 | MGMT | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | XRCC4 | 5 | 83353158 | T | A,G |
rs1056503 | 25178586 | 2067 | ERCC1 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | XRCC4 | 5 | 83353158 | T | A,G |
rs11082438 | 25279986 | 8170 | SLC14A2 | umls:C0024301 | GWASCAT | Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region. | 0.12 | 2014 | SLC14A2 | 18 | 45285245 | G | T |
rs113488022 | 25511147 | 673 | BRAF | umls:C0024301 | BeFree | The performance of the BRAF V600E-specific VE1 antibody was compared with that of allele-specific polymerase chain reaction (PCR) in 22 formalin-fixed, paraffin-embedded (FFPE) specimens with HCL involvement, along with nine splenic marginal zone lymphomas (SMZLs), 10 follicular lymphomas (FLs), 10 mantle cell lymphomas (MCLs), and 10 chronic lymphocytic leukemia/small lymphocytic lymphomas (CLL/SLLs). | 0.000271442 | 2015 | BRAF | 7 | 140753336 | A | T,G,C |
rs12711521 | 23055202 | 4155 | MBP | umls:C0024301 | BeFree | A SNP-based analysis showed that MBP rs8094402 was associated with decreased risks of overall NHL (allele risk OR = 0.72, P-trend = 0.0018), DLBCL (allele risk OR = 0.72, P-trend = 0.036), and FL (allele risk OR = 0.67, P-trend = 0.021), while MASP2 rs12711521 was associated with a decreased risk of DLBCL (allele risk OR = 0.57, P-trend = 0.0042). | 0.000271442 | 2013 | MASP2 | 1 | 11030859 | C | A |
rs12711521 | 23055202 | 10747 | MASP2 | umls:C0024301 | BeFree | A SNP-based analysis showed that MBP rs8094402 was associated with decreased risks of overall NHL (allele risk OR = 0.72, P-trend = 0.0018), DLBCL (allele risk OR = 0.72, P-trend = 0.036), and FL (allele risk OR = 0.67, P-trend = 0.021), while MASP2 rs12711521 was associated with a decreased risk of DLBCL (allele risk OR = 0.57, P-trend = 0.0042). | 0.000271442 | 2013 | MASP2 | 1 | 11030859 | C | A |
rs12917 | 25178586 | 7517 | XRCC3 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.008001298 | 2014 | MGMT | 10 | 129708019 | C | T |
rs12917 | 25178586 | 7518 | XRCC4 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | MGMT | 10 | 129708019 | C | T |
rs12917 | 25178586 | 675 | BRCA2 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | MGMT | 10 | 129708019 | C | T |
rs12917 | 25178586 | 2067 | ERCC1 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | MGMT | 10 | 129708019 | C | T |
rs12917 | 22430443 | 4255 | MGMT | umls:C0024301 | BeFree | After stratification by major NHL histological subtypes, MGMT (rs12917) modified the association between chlorinated solvents and the risk of diffuse large B-cell lymphoma (Pfor interaction=0.0027) and follicular lymphoma (Pfor interaction=0.0024). | 0.003181358 | 2012 | MGMT | 10 | 129708019 | C | T |
rs12917 | 25178586 | 7486 | WRN | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002909916 | 2014 | MGMT | 10 | 129708019 | C | T |
rs12917 | 25178586 | 5887 | RAD23B | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | MGMT | 10 | 129708019 | C | T |
rs12917 | 25178586 | 4255 | MGMT | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | MGMT | 10 | 129708019 | C | T |
rs13254990 | 25279986 | 596 | BCL2 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.343804516 | 2014 | PVT1 | 8 | 128064205 | C | T |
rs13254990 | 25279986 | 4026 | LPP | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | PVT1 | 8 | 128064205 | C | T |
rs13254990 | 25279986 | 5820 | PVT1 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | PVT1 | 8 | 128064205 | C | T |
rs13254990 | 25279986 | 5820 | PVT1 | umls:C0024301 | GWASCAT | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | PVT1 | 8 | 128064205 | C | T |
rs13254990 | 25279986 | 2113 | ETS1 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.000271442 | 2014 | PVT1 | 8 | 128064205 | C | T |
rs13254990 | 25279986 | 643 | CXCR5 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.000814326 | 2014 | PVT1 | 8 | 128064205 | C | T |
rs1346044 | 25178586 | 7486 | WRN | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002909916 | 2014 | WRN;LOC105379359 | 8 | 31167138 | T | C |
rs1346044 | 25178586 | 2067 | ERCC1 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | WRN;LOC105379359 | 8 | 31167138 | T | C |
rs1346044 | 25178586 | 675 | BRCA2 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | WRN;LOC105379359 | 8 | 31167138 | T | C |
rs1346044 | 25178586 | 7517 | XRCC3 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.008001298 | 2014 | WRN;LOC105379359 | 8 | 31167138 | T | C |
rs1346044 | 25178586 | 4255 | MGMT | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | WRN;LOC105379359 | 8 | 31167138 | T | C |
rs1346044 | 25178586 | 5887 | RAD23B | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | WRN;LOC105379359 | 8 | 31167138 | T | C |
rs1346044 | 25178586 | 7518 | XRCC4 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | WRN;LOC105379359 | 8 | 31167138 | T | C |
rs144848 | 25178586 | 675 | BRCA2 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | BRCA2 | 13 | 32332592 | A | C |
rs144848 | 21476145 | 675 | BRCA2 | umls:C0024301 | BeFree | Association of follicular lymphoma risk with BRCA2 N372H polymorphism in Slovak population. | 0.003181358 | 2012 | BRCA2 | 13 | 32332592 | A | C |
rs144848 | 21476145 | 3981 | LIG4 | umls:C0024301 | BeFree | We have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls. | 0.002638474 | 2012 | BRCA2 | 13 | 32332592 | A | C |
rs144848 | 25178586 | 7518 | XRCC4 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | BRCA2 | 13 | 32332592 | A | C |
rs144848 | 21476145 | 5896 | RAG1 | umls:C0024301 | BeFree | We have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls. | 0.002638474 | 2012 | BRCA2 | 13 | 32332592 | A | C |
rs144848 | 25178586 | 2067 | ERCC1 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | BRCA2 | 13 | 32332592 | A | C |
rs144848 | 25178586 | 7486 | WRN | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002909916 | 2014 | BRCA2 | 13 | 32332592 | A | C |
rs144848 | 25178586 | 5887 | RAD23B | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | BRCA2 | 13 | 32332592 | A | C |
rs144848 | 21476145 | 7486 | WRN | umls:C0024301 | BeFree | We have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls. | 0.002909916 | 2012 | BRCA2 | 13 | 32332592 | A | C |
rs144848 | 25178586 | 4255 | MGMT | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | BRCA2 | 13 | 32332592 | A | C |
rs144848 | 25178586 | 7517 | XRCC3 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.008001298 | 2014 | BRCA2 | 13 | 32332592 | A | C |
rs1494555 | 20952689 | 7124 | TNF | umls:C0024301 | BeFree | After stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma. | 0.006905599 | 2011 | IL7R | 5 | 35871088 | G | A |
rs1695 | 17454600 | 2950 | GSTP1 | umls:C0024301 | BeFree | We studied deletions of GSTM1 and GSTT1, and the GSTP1 Ile(105)Val polymorphism in 89 patients with follicular lymphoma (FL). | 0.005276948 | 2007 | GSTP1 | 11 | 67585218 | A | G |
rs17749561 | 25279986 | 5820 | PVT1 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | NA | 18 | 63115978 | G | A |
rs17749561 | 25279986 | 643 | CXCR5 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.000814326 | 2014 | NA | 18 | 63115978 | G | A |
rs17749561 | 25279986 | 596 | BCL2 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.343804516 | 2014 | NA | 18 | 63115978 | G | A |
rs17749561 | 25279986 | 2113 | ETS1 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.000271442 | 2014 | NA | 18 | 63115978 | G | A |
rs17749561 | 25279986 | 4026 | LPP | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | NA | 18 | 63115978 | G | A |
rs1805329 | 25178586 | 4255 | MGMT | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | RAD23B | 9 | 107322047 | C | T |
rs1805329 | 25178586 | 5887 | RAD23B | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | RAD23B | 9 | 107322047 | C | T |
rs1805329 | 25178586 | 7486 | WRN | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002909916 | 2014 | RAD23B | 9 | 107322047 | C | T |
rs1805329 | 25178586 | 7517 | XRCC3 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.008001298 | 2014 | RAD23B | 9 | 107322047 | C | T |
rs1805329 | 25178586 | 675 | BRCA2 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | RAD23B | 9 | 107322047 | C | T |
rs1805329 | 25178586 | 2067 | ERCC1 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | RAD23B | 9 | 107322047 | C | T |
rs1805329 | 25178586 | 7518 | XRCC4 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | RAD23B | 9 | 107322047 | C | T |
rs1805377 | 25178586 | 675 | BRCA2 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | XRCC4 | 5 | 83353124 | G | A |
rs1805377 | 25178586 | 7518 | XRCC4 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | XRCC4 | 5 | 83353124 | G | A |
rs1805377 | 25178586 | 4255 | MGMT | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | XRCC4 | 5 | 83353124 | G | A |
rs1805377 | 25178586 | 5887 | RAD23B | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | XRCC4 | 5 | 83353124 | G | A |
rs1805377 | 25178586 | 7486 | WRN | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002909916 | 2014 | XRCC4 | 5 | 83353124 | G | A |
rs1805377 | 25178586 | 7517 | XRCC3 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.008001298 | 2014 | XRCC4 | 5 | 83353124 | G | A |
rs1805377 | 25178586 | 2067 | ERCC1 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | XRCC4 | 5 | 83353124 | G | A |
rs1883832 | 20473910 | 958 | CD40 | umls:C0024301 | BeFree | Data from earlier studies that are part of this pooling study implicate a functional polymorphism (-1C>T, rs1883832) in the TNFRSF5 gene encoding CD40 in the etiology of follicular lymphoma. | 0.0089015 | 2011 | CD40 | 20 | 46118343 | T | C |
rs20541 | 20952689 | 7124 | TNF | umls:C0024301 | BeFree | After stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma. | 0.006905599 | 2011 | IL13 | 5 | 132660272 | A | G |
rs2227973 | 21476145 | 7486 | WRN | umls:C0024301 | BeFree | We have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls. | 0.002909916 | 2012 | RAG1 | 11 | 36575763 | A | G |
rs2227973 | 21476145 | 3981 | LIG4 | umls:C0024301 | BeFree | We have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls. | 0.002638474 | 2012 | RAG1 | 11 | 36575763 | A | G |
rs2227973 | 21476145 | 5896 | RAG1 | umls:C0024301 | BeFree | We have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls. | 0.002638474 | 2012 | RAG1 | 11 | 36575763 | A | G |
rs2230009 | 21476145 | 3981 | LIG4 | umls:C0024301 | BeFree | We have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls. | 0.002638474 | 2012 | WRN | 8 | 31064419 | G | A |
rs2230009 | 21476145 | 7486 | WRN | umls:C0024301 | BeFree | We have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls. | 0.002909916 | 2012 | WRN | 8 | 31064419 | G | A |
rs2230009 | 21476145 | 5896 | RAG1 | umls:C0024301 | BeFree | We have genotyped polymorphisms in the RAG1 (K820R), LIG4 (T9I), BRCA2 (N372H), and WRN (V114I) genes in 108 patients with histologically proven FL diagnosis and 127 healthy controls. | 0.002638474 | 2012 | WRN | 8 | 31064419 | G | A |
rs2308321 | 25178586 | 7486 | WRN | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002909916 | 2014 | MGMT;LOC105378559 | 10 | 129766800 | A | G |
rs2308321 | 25178586 | 2067 | ERCC1 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | MGMT;LOC105378559 | 10 | 129766800 | A | G |
rs2308321 | 25178586 | 7518 | XRCC4 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | MGMT;LOC105378559 | 10 | 129766800 | A | G |
rs2308321 | 25178586 | 4255 | MGMT | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | MGMT;LOC105378559 | 10 | 129766800 | A | G |
rs2308321 | 25178586 | 5887 | RAD23B | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | MGMT;LOC105378559 | 10 | 129766800 | A | G |
rs2308321 | 25178586 | 675 | BRCA2 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | MGMT;LOC105378559 | 10 | 129766800 | A | G |
rs2308321 | 25178586 | 7517 | XRCC3 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.008001298 | 2014 | MGMT;LOC105378559 | 10 | 129766800 | A | G |
rs2308327 | 25178586 | 5887 | RAD23B | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | MGMT;LOC105378559 | 10 | 129766906 | A | G |
rs2308327 | 25178586 | 7486 | WRN | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002909916 | 2014 | MGMT;LOC105378559 | 10 | 129766906 | A | G |
rs2308327 | 25178586 | 7518 | XRCC4 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | MGMT;LOC105378559 | 10 | 129766906 | A | G |
rs2308327 | 25178586 | 4255 | MGMT | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | MGMT;LOC105378559 | 10 | 129766906 | A | G |
rs2308327 | 25178586 | 7517 | XRCC3 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.008001298 | 2014 | MGMT;LOC105378559 | 10 | 129766906 | A | G |
rs2308327 | 25178586 | 2067 | ERCC1 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | MGMT;LOC105378559 | 10 | 129766906 | A | G |
rs2308327 | 25178586 | 675 | BRCA2 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | MGMT;LOC105378559 | 10 | 129766906 | A | G |
rs2647012 | 23025665 | 3126 | HLA-DRB4 | umls:C0024301 | BeFree | In recent genome-wide association studies (GWAS) of FL, several genetic susceptibility loci have been identified on chromosome 6p21.33 (rs6457327) and 6p21.32 (rs10484561, rs2647012) in the human leukocyte antigen class I and class II regions. | 0.001085767 | 2012 | NA | 6 | 32696681 | T | C |
rs2647012 | 24304973 | 129831 | RBM45 | umls:C0024301 | BeFree | We confirmed that FL-protective rs2647012-linked variants, in high linkage disequilibrium with the extended haplotype DRB1*15:01-DQA1*01:02-DQB1*06:02, correlate with increased HLA-DQB1 expression. | 0.000814326 | 2013 | NA | 6 | 32696681 | T | C |
rs2647012 | 22296171 | 129831 | RBM45 | umls:C0024301 | BeFree | Moreover, DRB1*15-DQA1*01-DQB1*06 was highly correlated with an established FL risk locus, rs2647012. | 0.000814326 | 2012 | NA | 6 | 32696681 | T | C |
rs2647012 | 22911334 | 266629 | SEC14L3 | umls:C0024301 | BeFree | The TAP2 SNP was strongly associated with follicular lymphoma (FL, OR = 1.82, 95%CI 1.46-2.26; p = 6.9 × 10(-8)), and was independent of other known loci (rs10484561 and rs2647012) from this region. | 0.000271442 | 2012 | NA | 6 | 32696681 | T | C |
rs2647012 | 21533074 | 3119 | HLA-DQB1 | umls:C0024301 | GAD | [GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma.] | 0.005276948 | 2011 | NA | 6 | 32696681 | T | C |
rs2681416 | 25279986 | 942 | CD86 | umls:C0024301 | GWASCAT | Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region. | 0.12 | 2014 | CD86 | 3 | 122098766 | G | A |
rs2855429 | 21148756 | 6015 | RING1 | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | COL11A2 | 6 | 33190412 | A | C |
rs2855429 | 21148756 | 6257 | RXRB | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | COL11A2 | 6 | 33190412 | A | C |
rs2855429 | 21148756 | 199 | AIF1 | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | COL11A2 | 6 | 33190412 | A | C |
rs2855429 | 21148756 | 7918 | GPANK1 | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | COL11A2 | 6 | 33190412 | A | C |
rs2857597 | 21148756 | 199 | AIF1 | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | AIF1 | 6 | 31617223 | T | A |
rs2857597 | 21148756 | 6257 | RXRB | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | AIF1 | 6 | 31617223 | T | A |
rs2857597 | 21148756 | 6015 | RING1 | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | AIF1 | 6 | 31617223 | T | A |
rs2857597 | 21148756 | 7918 | GPANK1 | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | AIF1 | 6 | 31617223 | T | A |
rs3020314 | 18636124 | 2099 | ESR1 | umls:C0024301 | BeFree | Four ESR1 SNPs were associated with follicular lymphoma (FL) in the U.S. study, with rs3020314 remaining associated with reduced risk of FL after multiple testing adjustments [odds ratio (OR) = 0.42, 95% confidence interval (CI) = 0.23-0.77) and replication in the German study (OR = 0.24, 95% CI = 0.06-0.94). | 0.000271442 | 2008 | ESR1 | 6 | 151949537 | C | T |
rs3115667 | 21148756 | 6257 | RXRB | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | NA | 6 | 31675622 | T | C |
rs3115667 | 21148756 | 199 | AIF1 | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | NA | 6 | 31675622 | T | C |
rs3115667 | 21148756 | 7918 | GPANK1 | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | NA | 6 | 31675622 | T | C |
rs3115667 | 21148756 | 6015 | RING1 | umls:C0024301 | BeFree | Accordingly, SNPs in RING1/RXRB (rs2855429), AIF1 (rs2857597), and BAT4 (rs3115667) were associated with NHL (P-trends ≤ 0.0002) and both diffuse large B-cell and follicular lymphomas (P-trends < 0.05). | 0.000271442 | 2011 | NA | 6 | 31675622 | T | C |
rs3212961 | 25178586 | 7517 | XRCC3 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.008001298 | 2014 | ERCC1 | 19 | 45419065 | G | T,A |
rs3212961 | 25178586 | 2067 | ERCC1 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | ERCC1 | 19 | 45419065 | G | T,A |
rs3212961 | 25178586 | 7486 | WRN | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002909916 | 2014 | ERCC1 | 19 | 45419065 | G | T,A |
rs3212961 | 25178586 | 5887 | RAD23B | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | ERCC1 | 19 | 45419065 | G | T,A |
rs3212961 | 25178586 | 7518 | XRCC4 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | ERCC1 | 19 | 45419065 | G | T,A |
rs3212961 | 25178586 | 4255 | MGMT | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | ERCC1 | 19 | 45419065 | G | T,A |
rs3212961 | 25178586 | 675 | BRCA2 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | ERCC1 | 19 | 45419065 | G | T,A |
rs3751913 | 25279986 | 79415 | C17orf62 | umls:C0024301 | GWASCAT | Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region. | 0.12 | 2014 | C17orf62 | 17 | 82447676 | T | C |
rs3789068 | 19336552 | 10018 | BCL2L11 | umls:C0024301 | BeFree | Variants in BCL2L11 were strongly related to follicular lymphoma only, particularly rs3789068 (OR(AG), 1.41; 95% CI, 1.10-1.81; OR(GG), 1.65; 95% CI, 1.25-2.19; P(trend) = 0.0004). | 0.002638474 | 2009 | BCL2L11 | 2 | 111151670 | A | G |
rs4645959 | 8012955 | 4609 | MYC | umls:C0024301 | BeFree | An unusual asparagine to serine mutation at codon 11 was identified in several transformed follicular lymphomas without MYC rearrangement but not in normal tissues from patients with this mutation. | 0.007524428 | 1994 | MYC | 8 | 127738294 | A | C,G |
rs4937362 | 25279986 | 5820 | PVT1 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | LOC105369568 | 11 | 128622844 | T | C |
rs4937362 | 25279986 | 643 | CXCR5 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.000814326 | 2014 | LOC105369568 | 11 | 128622844 | T | C |
rs4937362 | 25279986 | 2113 | ETS1 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.000271442 | 2014 | LOC105369568 | 11 | 128622844 | T | C |
rs4937362 | 25279986 | 4026 | LPP | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | LOC105369568 | 11 | 128622844 | T | C |
rs4937362 | 25279986 | 596 | BCL2 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.343804516 | 2014 | LOC105369568 | 11 | 128622844 | T | C |
rs4938573 | 25279986 | 2113 | ETS1 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.000271442 | 2014 | NA | 11 | 118871133 | C | T |
rs4938573 | 25279986 | 4026 | LPP | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | NA | 11 | 118871133 | C | T |
rs4938573 | 25279986 | 643 | CXCR5 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.000814326 | 2014 | NA | 11 | 118871133 | C | T |
rs4938573 | 25279986 | 596 | BCL2 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.343804516 | 2014 | NA | 11 | 118871133 | C | T |
rs4938573 | 25279986 | 5820 | PVT1 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | NA | 11 | 118871133 | C | T |
rs568408 | 20952689 | 7124 | TNF | umls:C0024301 | BeFree | After stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma. | 0.006905599 | 2011 | IL12A;IL12A-AS1 | 3 | 159995680 | G | A |
rs587776632 | NA | 8915 | BCL10 | umls:C0024301 | CLINVAR | NA | 0.122909916 | NA | BCL10 | 1 | 85267902 | - | AA |
rs587776633 | NA | 8915 | BCL10 | umls:C0024301 | CLINVAR | NA | 0.122909916 | NA | BCL10 | 1 | 85270733 | - | T |
rs587776634 | NA | 8915 | BCL10 | umls:C0024301 | CLINVAR | NA | 0.122909916 | NA | BCL10 | 1 | 85267788 | TGCCTACTTCTAGAACA | - |
rs587776635 | NA | 8915 | BCL10 | umls:C0024301 | CLINVAR | NA | 0.122909916 | NA | BCL10 | 1 | 85267919 | T | - |
rs587776636 | NA | 8915 | BCL10 | umls:C0024301 | CLINVAR | NA | 0.122909916 | NA | BCL10 | 1 | 85267931 | - | A |
rs587776637 | NA | 8915 | BCL10 | umls:C0024301 | CLINVAR | NA | 0.122909916 | NA | BCL10 | 1 | 85267692 | CTT | - |
rs601341 | 17169801 | 4361 | MRE11A | umls:C0024301 | BeFree | A protective effect against follicular lymphoma was seen for the MRE11 rs601341 variant, the homozygous T allele being associated with an odds ratio (OR) of 0.50, 95% confidence interval (95% CI) 0.26 - 0.97, while a protective effect was seen for the MRE11 haplotype GCTCA (OR 0.72, 95% CI 0.53 - 0.97) for diffuse large B-cell lymphoma. | 0.000271442 | 2006 | MRE11A | 11 | 94434611 | G | A |
rs6054706 | 23055202 | 81623 | DEFB126 | umls:C0024301 | BeFree | We also observed an increased risk of FL for DEFB126 rs6054706 (allele risk OR = 1.39, P-trend = 0.033). | 0.000271442 | 2013 | NA | 20 | 149223 | C | T |
rs6444305 | 25279986 | 643 | CXCR5 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.000814326 | 2014 | LPP | 3 | 188582114 | G | A |
rs6444305 | 25279986 | 2113 | ETS1 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.000271442 | 2014 | LPP | 3 | 188582114 | G | A |
rs6444305 | 25279986 | 5820 | PVT1 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | LPP | 3 | 188582114 | G | A |
rs6444305 | 25279986 | 4026 | LPP | umls:C0024301 | GWASCAT | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | LPP | 3 | 188582114 | G | A |
rs6444305 | 25279986 | 4026 | LPP | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.120271442 | 2014 | LPP | 3 | 188582114 | G | A |
rs6444305 | 25279986 | 596 | BCL2 | umls:C0024301 | BeFree | Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. | 0.343804516 | 2014 | LPP | 3 | 188582114 | G | A |
rs6457327 | 23025665 | 3126 | HLA-DRB4 | umls:C0024301 | BeFree | In recent genome-wide association studies (GWAS) of FL, several genetic susceptibility loci have been identified on chromosome 6p21.33 (rs6457327) and 6p21.32 (rs10484561, rs2647012) in the human leukocyte antigen class I and class II regions. | 0.001085767 | 2012 | NA | 6 | 31106253 | A | C |
rs6457327 | 20639881 | 285834 | HCG22 | umls:C0024301 | GAD | [Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.] | 0.004734064 | 2010 | NA | 6 | 31106253 | A | C |
rs6457327 | 19620980 | 285834 | HCG22 | umls:C0024301 | GAD | [Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma.] | 0.004734064 | 2009 | NA | 6 | 31106253 | A | C |
rs735665 | 20639881 | 79827 | CLMP | umls:C0024301 | GAD | [Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.] | 0.002367032 | 2010 | GRAMD1B | 11 | 123490689 | G | A |
rs735665 | 20639881 | 57476 | GRAMD1B | umls:C0024301 | GWASCAT | Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32. | 0.12 | 2010 | GRAMD1B | 11 | 123490689 | G | A |
rs737865 | 16214922 | 1312 | COMT | umls:C0024301 | BeFree | ORs for all non-Hodgkin lymphoma and follicular lymphoma among women were decreased for COMT IVS1 701A>G [rs737865; variant allele: OR, 0.53; 95% CI, 0.34-0.82; OR, 0.42; 95% CI, 0.23-0.78, respectively]. | 0.000271442 | 2005 | COMT;TXNRD2 | 22 | 19942598 | A | G |
rs8094402 | 23055202 | 4155 | MBP | umls:C0024301 | BeFree | A SNP-based analysis showed that MBP rs8094402 was associated with decreased risks of overall NHL (allele risk OR = 0.72, P-trend = 0.0018), DLBCL (allele risk OR = 0.72, P-trend = 0.036), and FL (allele risk OR = 0.67, P-trend = 0.021), while MASP2 rs12711521 was associated with a decreased risk of DLBCL (allele risk OR = 0.57, P-trend = 0.0042). | 0.000271442 | 2013 | MBP | 18 | 76995493 | A | G |
rs8094402 | 23055202 | 10747 | MASP2 | umls:C0024301 | BeFree | A SNP-based analysis showed that MBP rs8094402 was associated with decreased risks of overall NHL (allele risk OR = 0.72, P-trend = 0.0018), DLBCL (allele risk OR = 0.72, P-trend = 0.036), and FL (allele risk OR = 0.67, P-trend = 0.021), while MASP2 rs12711521 was associated with a decreased risk of DLBCL (allele risk OR = 0.57, P-trend = 0.0042). | 0.000271442 | 2013 | MBP | 18 | 76995493 | A | G |
rs861539 | 25178586 | 7486 | WRN | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002909916 | 2014 | KLC1;XRCC3 | 14 | 103699416 | G | A |
rs861539 | 25178586 | 675 | BRCA2 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | KLC1;XRCC3 | 14 | 103699416 | G | A |
rs861539 | 25178586 | 4255 | MGMT | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.003181358 | 2014 | KLC1;XRCC3 | 14 | 103699416 | G | A |
rs861539 | 25178586 | 7517 | XRCC3 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.008001298 | 2014 | KLC1;XRCC3 | 14 | 103699416 | G | A |
rs861539 | 25178586 | 7518 | XRCC4 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | KLC1;XRCC3 | 14 | 103699416 | G | A |
rs861539 | 25178586 | 2067 | ERCC1 | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | KLC1;XRCC3 | 14 | 103699416 | G | A |
rs861539 | 25178586 | 5887 | RAD23B | umls:C0024301 | BeFree | The following genotypes in combination with hair dye use before 1980 were associated with FL risk: BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70(1.30-5.65)], XRCC3 rs861539 CT+TT [OR(95% CI) 2.76(1.32-5.77)], XRCC4 rs1805377 GG [OR(95% CI) 2.07(1.10-3.90)] and rs1056503 TT [OR(95% CI) 2.17(1.16-4.07)], ERCC1 rs3212961 CC [OR(95% CI) 1.93(1.00-3.72)], RAD23B rs1805329 CC [OR(95% CI) 2.28(1.12-4.64)], and MGMT rs12917 CC, rs2308321 AA, and rs2308327 AA genotypes [OR(95% CI) 1.96(1.06-3.63), 2.02(1.09-3.75), and 2.23(1.16-4.29), respectively]. | 0.002638474 | 2014 | KLC1;XRCC3 | 14 | 103699416 | G | A |
rs9808753 | 20952689 | 7124 | TNF | umls:C0024301 | BeFree | After stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma. | 0.006905599 | 2011 | IFNGR2 | 21 | 33415005 | A | G |
GWASdb Annotation(Total Genotypes:0) | |
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(Waiting for update.) |
GWASdb Snp Trait(Total Genotypes:0) | |
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(Waiting for update.) |
Mapped by lexical matching(Total Items:2) | ||||
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HP ID | HP Name | MP ID | MP Name | Annotation |
HP:0002585 | Abnormality of the peritoneum | MP:0004500 | increased incidence of tumors by ionizing radiation induction | higher than normal frequency of tumor incidence induced by radiation in which the individual particle or photon carries sufficient energy to completely remove an electron from its orbit; common types of this radiation include gamma-rays and X-rays |
HP:0001824 | Weight loss | MP:0005114 | premature hair loss | release of fur at an earlier than expected time |
Mapped by homologous gene(Total Items:12) | ||||
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HP ID | HP Name | MP ID | MP Name | Annotation |
HP:0001945 | Fever | MP:0020254 | decreased collagen level | decreased level of the main structural protein of the various connective tissues in animals |
HP:0001824 | Weight loss | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
HP:0002202 | Pleural effusion | MP:0014233 | bile duct epithelium hyperplasia | |
HP:0100721 | Mediastinal lymphadenopathy | MP:0014169 | decreased brown adipose tissue mass | decreased physical bulk or volume of brown adipose tissue |
HP:0200036 | Skin nodule | MP:0013601 | increased testis apoptosis | increase in the number of cells of the male reproductive glands undergoing programmed cell death |
HP:0001287 | Meningitis | MP:0020215 | impaired blood coagulation | impaired ability of the blood to clot |
HP:0002585 | Abnormality of the peritoneum | MP:0014126 | increased mammary gland apoptosis | increase in the number of any cells of a mammary gland undergoing programmed cell death |
HP:0002716 | Lymphadenopathy | MP:0020215 | impaired blood coagulation | impaired ability of the blood to clot |
HP:0002665 | Lymphoma | MP:0020154 | impaired humoral immune response | impaired response of the immune system that mediates secreted antibodies produced in B cells |
HP:0001004 | Lymphedema | MP:0014171 | increased fatty acid oxidation | increased rate or incidence of the process of removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydr |
HP:0012378 | Fatigue | MP:0013659 | abnormal erythroid lineage cell morphology | any structural anomaly of an immature or mature cell in the lineage leading to and including erythrocytes |
HP:0001744 | Splenomegaly | MP:0020254 | decreased collagen level | decreased level of the main structural protein of the various connective tissues in animals |
Disease ID | 85 |
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Disease | follicular lymphoma |
Case | (Waiting for update.) |